GI EcologiX™

Gastrointestinal Health & Microbiome Profile

A clinical tool born from a collaboration between Phylo Bioscience™ and global consultancy of leading clinicians and researchers in host-microbiome science.

By Phylo Bioscience™ a CQC registered UK microbiome laboratory.

RRP: £339

GI EcologiX™ has been designed as a comprehensive GI health and microbiome profile that serves the clinician and their patients whilst aligning the methodology, technology and biomarkers with the latest developments in the microbiology space.

In designing this test – the science, the target markers, and its clinical utility – we approached leading European clinicians, consulted with Dr Jason Hawrelak and the Scientific Advisory Board at Phylo Bioscience™ and Invivo’s Clinical Advisory. We hope you are as excited as we are at the clinical potential of this diagnostic test.

Humphrey Bacchus,
Invivo MD | Phylo Founder

 

The Test


1 sample / 2 swabs
Quantitative real-time PCR (qRT-PCR)
Enzyme-linked immunosorbent assay (ELISA)
Endogenous control for normalisation and accuracy
5 x GI health markers (beta-defensin 2, calprotectin, elastase, SIgA, zonulin)
63 x target bacterial, fungal and parasite markers
SCFA producing bacteria (butyrate, propionate and acetate)
SIBO related bacteria (sulfidogenic and methanogenic bacteria)
H. pylori + stool antigen
Clinical resources (clinical considerations, interpretive guide, phyla guide, disease matrix)
Consultations for healthcare professionals

 

Order your GI EcologiX™

Methodology

Establishing a methodology that is the most accurate we currently know of in the microbiology field, and using the latest technology was absolutely critical for us in the development of the EcologiX™ profiles. For this, we established an incredibly knowledgeable and experienced Scientific Advisory Board to join the Phylo team, and dedicated time and money to create profiles we are all proud of.

The GI EcologiX™ profile uses quantitative realtime polymerase chain reaction (qRT-PCR), using TaqMan technology, to analyse the bacterial, fungal and viral communities of the gastrointestinal ecosystem. We also measure gastrointestinal health markers by enzyme linked immunosorbent assay (ELISA) technology.

Phylo have also added a couple of quality measures to ensure accuracy, which differ from other microbiome tests on the market. Phylo utilises a fixed amount of sample DNA (ng) per test and uses an endogenous control to measure your ‘baseline’ microbial load. This enables us to report accurately on the relative abundance of the target microbes.

Doing these extra steps means it is easier for you to compare your, or your patient’s samples before and after treatment.

Learn more about the science behind the EcologiX™ profiles

What We Measure

GI HEALTH MARKERS COMMENSAL BACTERIA (GRAM +/-)
Beta Defensin 2 Akkermansia muciniphila
Calprotectin Anaerostipes caccae
Elastase Bacteroides spp.
Secretory IgA Bifidobacterium spp.
Zonulin Escherichia coli
BACTEROIDES SUB GROUP Eubacterium rectale
Bacteroides dorei Faecalibacterium prausnitzii
Bacteroides fragilis Lactobacillus spp.
Bacteroides fragilis (Enterotoxigenic) Roseburia homini
Bacteroides ovatus Ruminococcus bromii
Bacteroides thetaiotaomicron Subdoligranulum variabile
Bacteroides uniformis CLOSTRIDIUM SUB GROUP
Bacteroides vulgatus Clostridium difficile
GRAM POSITIVE (+) BACTERIA Clostridium difficile (tox A)
Enterococcus faecalis Clostridium difficile (tox B)
Enterococcus faecium Clostridium perfringens
Enterococcus gallinarum Clostridium sporenges
Methanobrevibacter smithii GRAM NEGATIVE (-) BACTERIA
Mycobacterium avium Biophila wadsorthia
Ruminococcus gnavus Citrobacter freundii
Ruminococcus torques Citrobacter koseri
Staphylococcus aureus Citrobacter spp.
Streptococcus agalactiae Desulfovibrio
Streptococcus pneumoniae Enterobacter aerogenes
Streptococcus pyogenes Enterobacter cloacae
HELICOBACTER PYLORI Fusobacterium nucleatum
Helicobacter pylori Hafnia alvei
H. pylori stool antigen (confirmatory reflex) Klebsiella oxytoca
PARASITOLOGY Klebsiella pneumoniae
Blastocystis hominis Morganella morganii
Dientamoeba fragilis Oxalobacter formigenes
Entamoeba histolytica Prevotella spp.
Giardia Proteus mirabilis
MYCOLOGY Pseudomonas aeruginosa
Aspergillus fumigatus Serratia marcescens
Candida albicans Veillonella spp.
Candida krusei Yersinia enterocolitica
Candida tropicalis
Malassezia restricta

 

Download Sample Report

 

Test Indications


○ IBS/IBD
○ Autoimmune conditions
○ Neurodegeneration and Neurodevelopmental conditions
○ Depression
○ Chronic fatigue/fibromyalgia
○ SIBO
○ Chronic disease

Works Well With

For comprehensive multiple microbiome diagnostics & therapeutics