GI EcologiX™

Gastrointestinal Health & Microbiome Profile

A clinical tool born from a collaboration between the Invivo Laboratory and global consultancy of leading clinicians and researchers in host-microbiome science.

By Invivo in our CQC-approved, B Corp-certified, UK microbiome laboratory.

GI EcologiX™: the ultimate in science, clinical utility, and integrity.

Our aim from the beginning was to elevate the science (methodology, technology, and biomarkers) found in gut microbiome tests, to that in the microbiology field.

We will never put profit above purpose. And our purpose is – and always has been – to provide you with clinical tools for best patient outcomes. We have an uncompromising adherence to the science, and a strong belief in what we are doing.

We asked ourselves: what makes a GI test clinically useful; what do we, as healthcare providers, really need to take away from a gut test result? In the GI EcologiX, we stripped away the unnecessaries – the ‘noise’ – added key health and microbial markers with robust science and links to common symptoms and conditions such as SIBO and intestinal health integrity.

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The Test

15 working day turnaround time
All markers come as standard
Reference Ranges across all microbiome targets
1 sample / 3 swabs
Quantitative real-time PCR (qPCR)
Protein-based assays
7 x GI health markers (beta-defensin 2, calprotectin, pancreatic elastase 1, SIgA, zonulin, bile acids, occult blood-FIT) as standard
62 x target bacterial, fungal, and parasite markers
SCFA producing bacteria (butyrate, propionate, and acetate)
SIBO related bacteria (sulfidogenic and methanogenic bacteria)
H. pylori antigen
Mucin degrading Bacteroides sub-group
Pathogenic Bacteria sub-group
Interpretive support for healthcare professionals
B Corp-certified
Carbon neutral
CQC-approved (Care Quality Control)
Working towards ISO certification – the highest laboratory standard in the world

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Establishing a methodology that is the most accurate we currently know of in the microbiology field, and using the latest technology was absolutely critical for us in the development of the EcologiX™ profiles. For this, we established an incredibly knowledgeable and experienced Scientific Advisory Board to join the laboratory team, and dedicated time and money to create profiles that are the ultimate in science, clinical utility, and integrity.

The GI EcologiX™ profile uses quantitative real-time polymerase chain reaction (qPCR), using TaqMan technology, which offers superior sensitivity, specificity, and reproducibility. We also measure gastrointestinal health markers by a range of protein-based assays. The sample collection devices underwent extensive validation to ensure optimal DNA yields.

Learn more about the science behind the EcologiX™ profiles

What We Measure

Beta Defensin 2 Akkermansia muciniphila
Calprotectin Anaerostipes caccae
Pancreatic Elastase Bacteroides spp.
Secretory IgA Bifidobacterium spp.
Zonulin Blautia obeum
Bile acids Coprococcus eutactus
Occult blood (FIT) Escherichia coli
BACTEROIDES SUB GROUP Eubacterium rectale
Bacteroides dorei Faecalibacterium prausnitzii
Bacteroides fragilis Lactobacillus spp.
Bacteroides ovatus Roseburia homini
Bacteroides thetaiotaomicron Ruminococcus bromii
Bacteroides uniformis Subdoligranulum variabile
Bacteroides vulgatus GRAM NEGATIVE (-) BACTERIA
GRAM POSITIVE (+) BACTERIA Bilophila wadsworthia
Clostridium perfringens Citrobacter freundii
Clostridium sporogenes Citrobacter koseri
Enterococcus faecalis Desulfovibrio spp.
Enterococcus faecium Enterobacter cloacae
Enterococcus gallinarum Fusobacterium nucleatum
Methanobrevibacter smithii Hafnia alvei
Mycobacterium avium Klebsiella oxytoca
Ruminococcus gnavus Klebsiella pneumoniae
Ruminococcus torques Morganella morganii
Staphylococcus aureus Oxalobacter formigenes
Streptococcus agalactiae Prevotella scopri
Streptococcus pneumoniae Proteus mirabilis
Streptococcus pyogenes Pseudomonas aeruginosa
HELICOBACTER PYLORI Serratia marcescens
H. pylori antigen Veillonella spp.
Blastocystis hominis Bacteroides fragilis (Enterotoxigenic)
Dientamoeba fragilis Yersinia enterocolitica
Entamoeba histolytica Clostridium difficile
Giardia lamblia Clostridium difficile (tox A)
MYCOLOGY Clostridium difficile (tox B)
Aspergillus fumigatus
Candida albicans
Candida tropicalis
Malassezia restricta

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Test Indications

○ Digestive complaints, such as bloating
○ Autoimmune conditions
○ Neurodegeneration and neurodevelopmental conditions
○ Depression & ‘foggy brain’
○ Chronic fatigue/fibromyalgia
○ Chronic disease

Works Well With

For comprehensive multiple microbiome tests & supplements