GI EcologiX™

Gastrointestinal Health & Microbiome Profile

A clinical tool born from a collaboration between Invivo Diagnostics Laboratory and global consultancy of leading clinicians and researchers in host-microbiome science.

By Invivo Diagnostics, our CQC-approved, B Corp-certified, UK microbiome laboratory.

RRP: £339

GI EcologiX™: the ultimate in science, clinical utility, and integrity.

SCIENCE
Our aim from the beginning was to elevate the science (methodology, technology, and biomarkers) found in gut microbiome tests, to that in the microbiology field.

INTEGRITY
We will never put profit above purpose. And our purpose is – and always has been – to provide you with clinical tools for best patient outcomes. We have an uncompromising adherence to the science, and a strong belief in what we are doing.

CLINICAL UTILITY
We asked ourselves: what makes a GI test clinically useful; what do we, as healthcare providers, really need to take away from a gut test result? In the GI EcologiX, we stripped away the unnecessaries – the ‘noise’ – added key health and microbial markers with robust science and links to common symptoms and conditions such as SIBO and intestinal health integrity.

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The Test


15 working day turnaround time
All markers come as standard
1 sample / 3 swabs
Quantitative real-time PCR (qPCR)
Protein-based assays
7 x GI health markers (beta-defensin 2, calprotectin, pancreatic elastase 1, SIgA, zonulin, bile acids, occult blood-FIT) as standard
63 x target bacterial, fungal, and parasite markers
SCFA producing bacteria (butyrate, propionate, and acetate)
SIBO related bacteria (sulfidogenic and methanogenic bacteria)
H. pylori + stool antigen
Mucin degrading Bacteroides sub-group
Clostridium sub-group
Interpretive support for healthcare professionals
B Corp-certified
Carbon neutral
CQC-approved (Care Quality Control)
Working towards ISO certification – the highest laboratory standard in the world

 

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Methodology

Establishing a methodology that is the most accurate we currently know of in the microbiology field, and using the latest technology was absolutely critical for us in the development of the EcologiX™ profiles. For this, we established an incredibly knowledgeable and experienced Scientific Advisory Board to join the laboratory team, and dedicated time and money to create profiles that are the ultimate in science, clinical utility, and integrity.

The GI EcologiX™ profile uses quantitative real-time polymerase chain reaction (qPCR), using TaqMan technology, which offers superior sensitivity, specificity, and reproducibility. We also measure gastrointestinal health markers by a range of protein-based assays. The sample collection devices underwent extensive validation to ensure optimal DNA yields.

Learn more about the science behind the EcologiX™ profiles

What We Measure

GI HEALTH MARKERS COMMENSAL BACTERIA (GRAM +/-)
Beta Defensin 2 Akkermansia muciniphila
Calprotectin Anaerostipes caccae
Pancreatic Elastase Bacteroides spp.
Secretory IgA Bifidobacterium spp.
Zonulin Escherichia coli
Bile acids Eubacterium rectale
Occult blood (FIT) Faecalibacterium prausnitzii
BACTEROIDES SUB GROUP Lactobacillus spp.
Bacteroides dorei Roseburia homini
Bacteroides fragilis Ruminococcus bromii
Bacteroides fragilis (Enterotoxigenic) Subdoligranulum variabile
Bacteroides ovatus CLOSTRIDIUM SUB GROUP
Bacteroides thetaiotaomicron Clostridium difficile
Bacteroides uniformis Clostridium difficile (tox A)
Bacteroides vulgatus Clostridium difficile (tox B)
GRAM POSITIVE (+) BACTERIA Clostridium perfringens
Enterococcus faecalis Clostridium sporogenes
Enterococcus faecium GRAM NEGATIVE (-) BACTERIA
Enterococcus gallinarum Bilophila wadsworthia
Methanobrevibacter smithii Citrobacter freundii
Mycobacterium avium Citrobacter koseri
Ruminococcus gnavus Citrobacter spp.
Ruminococcus torques Desulfovibrio spp.
Staphylococcus aureus Enterobacter aerogenes
Streptococcus agalactiae Enterobacter cloacae
Streptococcus pneumoniae Fusobacterium nucleatum
Streptococcus pyogenes Hafnia alvei
HELICOBACTER PYLORI Klebsiella oxytoca
Helicobacter pylori Klebsiella pneumoniae
H. pylori stool antigen (confirmatory reflex) Morganella morganii
PARASITOLOGY Oxalobacter formigenes
Blastocystis hominis Prevotella spp.
Dientamoeba fragilis Proteus mirabilis
Entamoeba histolytica Pseudomonas aeruginosa
Giardia lamblia Serratia marcescens
MYCOLOGY Veillonella spp.
Aspergillus fumigatus Yersinia enterocolitica
Candida albicans
Candida krusei
Candida tropicalis
Malassezia restricta

 

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Test Indications


○ IBS/IBD
○ Digestive complaints, such as bloating
○ Autoimmune conditions
○ Neurodegeneration and neurodevelopmental conditions
○ Depression & ‘foggy brain’
○ Chronic fatigue/fibromyalgia
○ SIBO
○ Chronic disease

Works Well With

For comprehensive multiple microbiome diagnostics & therapeutics