GI EcologiX™

Gastrointestinal Health & Microbiome Profile

A clinical tool born from a collaboration between Invivo Diagnostics Laboratory and global consultancy of leading clinicians and researchers in host-microbiome science.

By Invivo Diagnostics, our CQC-approved, B Corp-certified, UK microbiome laboratory.

RRP: £339

GI EcologiX™ is a comprehensive GI health and microbiome profile that serves the clinician and their patients whilst aligning the methodology, technology and biomarkers with the latest developments in the microbiology space.

In designing this test – the science, the target markers, and its clinical utility – we approached leading European clinicians, consulted with Dr Jason Hawrelak and the Scientific Advisory Board at Invivo Diagnostics and Invivo’s Clinical Advisory. The aim from day one was to produce the world’s best microbiome profile for the ultimate in clinical utility and scientific integrity.

Humphrey Bacchus,
Invivo Healthcare MD | Invivo Diagnostics Founder

 

The Test


15 working day turnaround time
All markers come as standard
1 sample / 2 swabs
Quantitative real-time PCR (qPCR)
Enzyme-linked immunosorbent assay (ELISA)
5 x GI health markers (beta-defensin 2, calprotectin, pancreatic elastase, SIgA, zonulin) as standard
63 x target bacterial, fungal and parasite markers
SCFA producing bacteria (butyrate, propionate, and acetate)
SIBO related bacteria (sulfidogenic and methanogenic bacteria)
H. pylori + stool antigen
Mucin degrading Bacteroides sub-group
Clostridium sub-group
Interpretive support for healthcare professionals
B Corp-certified
Carbon neutral
CQC-approved (Care Quality Control)
Working towards ISO certification – the highest laboratory standard in the world

 

Order your GI EcologiX™

Methodology

Establishing a methodology that is the most accurate we currently know of in the microbiology field, and using the latest technology was absolutely critical for us in the development of the EcologiX™ profiles. For this, we established an incredibly knowledgeable and experienced Scientific Advisory Board to join the laboratory team, and dedicated time and money to create profiles that are the ultimate in science, clinical utility, and integrity.

The GI EcologiX™ profile uses quantitative real-time polymerase chain reaction (qPCR), using TaqMan technology, which offers superior sensitivity, specificity, and reproducibility. We also measure gastrointestinal health markers by enzyme-linked immunosorbent assay (ELISA) technology. The sample collection devices underwent extensive validation to ensure optimal DNA yields.

We take a fixed amount of sample DNA (ng) to analyse, as opposed to a fixed weight of sample. This removes variables such as water and fibre content, which can significantly alter the weight of the sample, the extractable DNA and leads to inaccurate results.

Learn more about the science behind the EcologiX™ profiles

What We Measure

GI HEALTH MARKERS COMMENSAL BACTERIA (GRAM +/-)
Beta Defensin 2 Akkermansia muciniphila
Calprotectin Anaerostipes caccae
Pancreatic Elastase Bacteroides spp.
Secretory IgA Bifidobacterium spp.
Zonulin Escherichia coli
BACTEROIDES SUB GROUP Eubacterium rectale
Bacteroides dorei Faecalibacterium prausnitzii
Bacteroides fragilis Lactobacillus spp.
Bacteroides fragilis (Enterotoxigenic) Roseburia homini
Bacteroides ovatus Ruminococcus bromii
Bacteroides thetaiotaomicron Subdoligranulum variabile
Bacteroides uniformis CLOSTRIDIUM SUB GROUP
Bacteroides vulgatus Clostridium difficile
GRAM POSITIVE (+) BACTERIA Clostridium difficile (tox A)
Enterococcus faecalis Clostridium difficile (tox B)
Enterococcus faecium Clostridium perfringens
Enterococcus gallinarum Clostridium sporogenes
Methanobrevibacter smithii GRAM NEGATIVE (-) BACTERIA
Mycobacterium avium Bilophila wadsworthia
Ruminococcus gnavus Citrobacter freundii
Ruminococcus torques Citrobacter koseri
Staphylococcus aureus Citrobacter spp.
Streptococcus agalactiae Desulfovibrio spp.
Streptococcus pneumoniae Enterobacter aerogenes
Streptococcus pyogenes Enterobacter cloacae
HELICOBACTER PYLORI Fusobacterium nucleatum
Helicobacter pylori Hafnia alvei
H. pylori stool antigen (confirmatory reflex) Klebsiella oxytoca
PARASITOLOGY Klebsiella pneumoniae
Blastocystis hominis Morganella morganii
Dientamoeba fragilis Oxalobacter formigenes
Entamoeba histolytica Prevotella spp.
Giardia spp. Proteus mirabilis
MYCOLOGY Pseudomonas aeruginosa
Aspergillus fumigatus Serratia marcescens
Candida albicans Veillonella spp.
Candida krusei Yersinia enterocolitica
Candida tropicalis
Malassezia restricta

 

Download Sample Report

 

Test Indications


○ IBS/IBD
○ Digestive complaints, such as bloating
○ Autoimmune conditions
○ Neurodegeneration and neurodevelopmental conditions
○ Depression & ‘foggy brain’
○ Chronic fatigue/fibromyalgia
○ SIBO
○ Chronic disease

Works Well With

For comprehensive multiple microbiome diagnostics & therapeutics