Oral EcologiX™

Oral Health & Microbiome Profile

A ground-breaking clinical tool for the assessment of the oral microbiome – a key ecosystem in the gut-brain connection, and for cardiovascular and female reproductive health.

By Invivo Diagnostics, our CQC registered UK microbiome laboratory.

RRP: £129

The Oral Microbiome

The oral cavity is a complex ecosystem, comprising several habitats including the teeth, gums, tongue and tonsils, all colonised by bacteria. The oral microbiota consists of approximately 600 taxa at the species level, with different groups and subsets inhabiting different niches.

The microbiota of the oral cavity exists as a complex biofilm that remains stable, despite environmental changes. However, dysbiosis, in form of infection, injury, dietary changes and risk-associated factors (e.g. smoking) may disrupt the biofilm community, favouring colonisation and invasion of pathogens.

Disruption of the biofilm community to a pathogenic profile, induces host immune responses, chronic inflammation and ultimately, the development of local and systemic disease. However, much of this damage is reversible if pathogenic communities are reduced, and homeostasis is restored.

Read more about oral dysbiosis and the red, orange and bridge complexes

What We Measure

Commensal Bacteria (Orange Complex & Bridge Species) Classification
Campylobacter rectus Gram-negative
Eubacterium nodatum Gram-positive
Fusobacterium nucleatum Gram-negative
Lactobacillus spp. Gram-positive
Parvimonas micra Gram-positive
Peptostreptococcus anaerobius Gram-positive
Prevotella intermedia Gram-negative
Prevotella nigrescens Gram-negative
Streptococcus mutans Gram-positive
Pathogens (Red Complex) Classification
Aggregatibacter actinomycetemcomitans Gram-negative
Porphyromonas gingivalis Gram-positive
Tannerella forsythia Gram-negative
Treponema denticola Gram-negative
Fungi Classification
Candida albicans N/A

 

Download Sample Report

Methodology

Establishing a methodology that is the most accurate we currently know of in the microbiology field, and using the latest technology was absolutely critical for us in the development of the EcologiX™ profiles. For this, we established an incredibly knowledgeable and experienced Scientific Advisory Board to join the Invivo Diagnostics Laboratory team, and dedicated time and money to create profiles we are all proud of.

We use quantitative realtime polymerase chain reaction (qPCR), using TaqMan technology, to analyse the bacterial and fungal communities of the oral cavity.

We have also added a couple of quality measures to ensure accuracy, which differ from other microbiome tests on the market. We utilise a fixed amount of DNA (ng) from the sample and uses an endogenous control to measure your ‘baseline’ microbial load. This enables us to report accurately on the relative abundance of the target microbes.

Doing these extra steps means it is easier for you to compare your, or your patient’s samples before and after treatment.

Learn more about the science behind the EcologiX™ profiles

Test Indications


○ Oral health optimisation
○ Periodontitis/caries
○ Neurodegenerative disorders
○ Cardiovascular disease
○ Pregnancy optimisation
○ Oral candidiasis
○ Oral cancer

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