- Helicobacter pylori
- Virulence Factor, babA
- Virulence Factor, cagA
- Virulence Factor, dupA
- Virulence Factor, iceA
- Virulence Factor, oipA
- Virulence Factor, vacA
- Virulence Factor, virB
- Virulence Factor, virD
- Antibiotic Resistance Genes
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This test measures Helicobacter pylori (H. pylori) and two of its most well recognised virulence genes, cagA (cytotoxin-associated protein A) and vacA (vacuolating toxin).
H. pylori colonisation has been implicated in a variety of gastro-duodenal diseases including gastritis, gastric cancer, and duodenal and peptic ulcer. H. pylori has also been detected by stool PCR in cases of dyspepsia, abdominal pain, and chronic gastrointestinal symptoms.
However, H. pylori is a commensal organism and may protect its host from certain atopic disorders, as well as other diseases such as eosophageal cancer reflux, and obesity.
Whether H. pylori may cause harm may lie in its genetics, as well as the host’s immune status and acid secretion.
The presence of cagA-positive H.pylori strains has been significantly associated with gastric cancer and peptic ulcer.
The presence of vacA has been associated with gastric cancer, peptic ulcer, and duodenal ulcer.
Sample type: Stool
Turnaround time: 10 days
Lab: Diagnostic Solutions