The gut plays a central role in our innate immute system. A dysbiotic microbiota engendered by stress, ageing, antibiotics etc., impacts negatively on intestinal permeability and promotes endotoxemia. This chronic, low-grade inflammation mobilises the immune response and may negatively impact our ability to evade pathogens.
Galactooligosaccharides (GOS) is one of our key supplements to promote a healthy microbiome for immune health and host-microbiome homeostasis.
Prebiotic Intake for Optimal Immune Function
Human milk oligosaccharides (HMOs) are complex sugars representing the third-largest solid component in human milk after fat and lactose. Among them, galactooligosaccharides (GOS) are demonstrated to be an efficient prebiotic solution:
- Non-digestible, short-chain soluble fibres,
- Resistant to gastric acids and hydrolysis by human enzymes
- Resistant over time
- Selectively utilised by Bifidobacteria & Lactobacilli, which have established health benefits
Bio.Me™ Prebio GOS offers galactooligosaccharides with 9% 4’-galactosyllactose, a unique HMO with a proven beneficial effect on the regulation of gut microflora at a low dose.
GOS For The Enhancement of Innate Immune Function
The prebiotic functions of GOS at 70% concentration have a beneficial effect on the key stages of innate immunity by their action on barrier function and chronic low-grade inflammation. This helps balance the immune system, optimising its response when needed.
STEP 1: GOS direct effects on gut barrier function
GOS are effective in the transfer epithelium. GOS may improve physical intestinal barrier function, via its direct effects on:
- The inhibition of pathogenic bacteria adhesion
- Tight junction reinforcement
STEP 2: Modulation of gram positive bacteria population
GOS promotes biodiversity by amplifying beneficial Gram-positive lactic acid bacteria and Bifidobacteria growth, which decreases LPS-associated low-grade inflammation.
STEP 3: Healthy microbiota for optimal anti-inflammatory response
GOS modulates innate cell recruitment and promotes a healthy inflammatory response, contributing to the homeostasis of the immune system and enabling optimal immune function at times of need.
- 70% concentrated GOS, including 9% of 4’-galactosyllactose
- Patented ingredient
- Food-based & GRAS certified, GMO-free, gluten-free, Halal certification
- Soluble & neutral taste
- Indicated for bowel symptoms, immune health and skin health